22-P002 A cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: Specific contribution of GATA3
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چکیده
منابع مشابه
22-P002 A cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: Specific contribution of GATA3
The precise expression of the N-myc proto-oncogene is essential for normal mammalian development, whereas altered N-myc gene regulation is known to be a determinant factor in tumor formation. Using transgenic mouse embryos, we show that N-myc sequences from kb -8.7 to kb +7.2 are sufficient to reproduce the N-myc embryonic expression profile in developing branchial arches and limb buds. These s...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.1213